EIGHTH RTP RODENT PATHOLOGY COURSE

 

 Current Topics in Rodent Pathology

September 17 - 19, 2017 • Raleigh, North Carolina


SUNDAY, September 17, 2017
12:00 - 1:00pm Registration

SESSION I: Reproducibility of Animal Research Studies

1:00 - 1:45pm Introduction and Overview – Increasing rigor and reproducibility: lessons learned from the Reproducibility Project: Cancer Biology (via internet)

Courtney Soderberg, PhD

Center for Open Science

1:45 - 2:30pm Pathology as a variable in reproducibility

Jerrold M. Ward, DVM, PhD, DACVP, FIATP
Veterinary Pathologist

Global VetPathology

2:30 - 2:45pm Coffee / Tea
2:45 - 3:30pm The importance of controlling for stress in reproducibility of studies focused on endocrine endpoints Heather Patisaul, PhD
Professor, Biological Sciences
Center for Human Health and the Environment
WM Keck Center for Behavioral Biology
3:30 - 4:30pm Grading/scoring of naturally occurring and induced lesions in common mouse models

Cynthia Shackelford, DVM
Senior Pathologist
Experimental Pathology Laboratories, Inc

4:30 - 5:15pm Theory and approaches to automated image analysis in digital pathology Kyle Takayama, MS, Charles River Labs
5:15pm Opening Reception (heavy hors d'oeuvres)
MONDAY, September 18, 2017
7:30am - 12:00pm Registration
7:30am - 8:30am Coffee / Tea
SESSION II: Embryology and Developmental Pathology
8:30 - 8:35am Introduction to Session II  
8:35 - 9:15am The Developing Mouse: The Three P's – Prepare, Process, Position!

Susan Newbigging, BSc, MSc, DVM, DVSc​
Mt. Sinai Hospital

9:15 - 10:00am Principles and Practices for Evaluating Lethal Phenotypes

Brad Bolon, DVM, MS, PhD, DACVP, DABT, FATS, FIATP

GEMpath, Inc.

10:00 - 10:30am Break
10:30 - 11:15am Pathology of the Mouse Placenta: Everything You Wanted to Know But Didn’t Care to Ask

Jerrold M. Ward, DVM, PhD, DACVP, FIATP
Veterinary Pathologist

Global VetPathology

11:15 - 12:00pm Fetal Alcohol Spectrum Disorders in Mice

Kathy Sulik, PhD

University of North Carolina- Chapel Hill

12:00 - 1:00pm Lunch (included)
SESSION III: Humanized Mouse Models
1:15 - 2:00pm Background/overview humanized mouse models and husbandry

Zachary Freeman, DVM

University of Michigan

2:00 - 2:15pm Break
2:15 - 3:00pm Pathology of the humanized mice

Rich Peterson, DVM, PhD, DACVP

Abbvie

3:00 - 3:45pm Humanized mice (BLT mouse) used in research such as HIV

Martina Kovarova, PhD

University of North Carolina- Chapel Hill

3:45 - 4:30pm Immuno-oncology research

Paula Miliani de Marval, PhD Charles River Laboratories

TUESDAY, September 19, 2017
SESSION IV: Microbiota and Animal Models of Intestinal Disease
7:30am - 8:30am Coffee / Tea
8:30 - 8:35am Introduction to Session IV  
8:35 - 9:15am Discovering the Microbiome M. Andrea Azcarate-Peril, University of North Carolina-Chapel Hill
9:15 - 10:00am Therapeutic Targets in the Gut Microbiome

Matt Redinbo, University of North Carolina-Chapel Hill

10:00 - 10:30am Break
10:30 - 11:15am Murine Models of IBD

Laura Hale, MD, PhD

Duke University

11:15 - 12:00pm The Impact of the Gut Microbiota on Murine Models of Human Disease Allison Rogala, University of North Carolina-Chapel Hill
12:00 - 1:00pm Lunch (provided)

SESSION V: Pathology in Practice: Evolving Methods and Techniques

1:00 - 1:45pm Immunoassays: What, How, Why? Michelle Cora, DVM, DACVP NTP/NIEHS
1:45 - 2:30pm Basic Principles of Stereology and its Application in Animal Model Development

Danielle Brown, DVM, MS, DACVP, DABT

Charles River Laboratories

2:30 - 2:45pm Break
2:45 - 3:30pm MALDI Imaging MS: visualizing molecular histology in drug development

Steve Castellino, PhD

GalaxoSmithKline

3:30 - 4:15pm Magnetic Resonance Histology

G. Allan Johnson, PhD, Charles E Putman Professor of Radiology & Biomedical Engineering
Duke Center for IN vivo Microscopy

4:15 - 4:30pm

Meeting Closing Remarks